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William Holmes

Fogarty Life Science (FLS) 234
(401) 456-6325
(401) 456-8010

Academic Background

Ph.D. Brown University

Courses Taught


Research Interests

Protein Folding and Toxicity in Neurodegenerative Diseases


Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding. Nature Communications 5 (2014): 4383

Defining the Limits: Protein Aggregation and Toxicity In Vivo. Critical Reviews in Biochemistry and Molecular Biology 49 (2014): 294-303.

Crystal Structure of inositol phosphate multikinase 2 and implications for substrate specificity. J. Biol. Chem. 281 (2006): 38109-38116.​​​

Page last updated: July 10, 2017